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Rapid relief from inflammation and pruritus

Cortavance® is a potent topical steroid, containing HCA, for the symptomatic treatment of inflammatory and pruritic skin disorders

Product features & benefits:

  • Recommended by the International Committee on Allergic Diseases of Animals1
  • A topical treatment targeting the skin and nowhere else
  • Treat up to a third of the body at a time, every day at dose level
  • Cortavance® can be used for long-term management of atopic dermatitis
  • No known incompatibilities
  • Negligible side effects
  • Cortavance® acts only in the skin and contains HCA, which is 30 times more potent than hydrocortisone
  • There is NO transdermal absorption at dose level with negligible side effects at dose level
  • HCA is highly lipophilic, absorbed rapidly into the dermal layer, creating a concentrated reservoir effect of active ingredients
  • Avoiding the side effects associated with systemic therapy


Presentations available:

  • 31ml
  • 76ml


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Use medicines responsibly.
Further information is available on the SPC or on request from Virbac Ltd.


1. Olivry T, DeBoer DJ, Favrot C, et al. Treatment of canine atopic dermatitis: 2010 clinical practice guidelines from the International Task Force on Canine Atopic Dermatitis.Vet Dermatol. 2010;21(3):233–248.

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Product FAQ

  • 1. What is Cortavance?

    Cortavance spray is a topically applied veterinary medicine used to treat inflamed and itchy skin conditions in dogs and for alleviation of clinical signs associated with atopic dermatitis in dogs. It contains the active substance hydrocortisone aceponate, a locally active potent glucocorticoid.

  • 2. What is the dose rate?

    Two pump spray activations over a surface to be treated equivalent to a square of 10 cm x 10 cm. Repeat the treatment daily for 7 consecutive days.

  • 3. What is the safety profile of Cortavance?

    HCA spray has a good safety profile. There were no changes to haematology, biochemistry, adrenal function or skin thickness in safety studies where up to 1/3 of the body surface area of healthy dogs was treated daily for up to eight weeks. In addition, no adverse effects or altered haematology, biochemistry and ACTH stimulation tests were seen in dogs treated in clinical trials for up to 70 days. One recent study, however, noted some thinning of the abdominal skin, so careful monitoring of dogs treated in this area is advised.

  • 4. What is the shelf life of Cortavance once opened?

    The product should be used within 6 months after opening and before the date of expiry.

  • 5. Can I use Cortavance in pregnant animals?

    Although the safety of the veterinary medicinal product has not been established during pregnancy and lactation the systemic absorption of hydrocortisone aceponate is negligible and it is unlikely to be teratogenic, foetotoxic or maternotoxic at the recommended dosage in dogs. Use only accordingly to the risk-benefit assessment by the responsible veterinarian.

  • 6. Can I use Cortavance with other medicines?

    As there is negligible systemic absorption at the label dose rates the risk of interaction is minimal. It is recommended that other topical medicines are not applied at the same site as the Cortavance treatment area.